Felson et al. (1) Compared articles published in Arthritis and Rheumatism in 1982 and 1967-168 with regard to the use of statistical methods and statistical misuse.

Of the articles published in 1982 using statistical methods 66% had methodological errors.  In 1967-1968 fewer articles used statistics but of these the percentage with methodological errors was similar. The most common error in 1967-1968 was failure to identify the statistical method used. In 1982 the main problem was multiple testing errors.

The authors recommend using ANOVA instead of repeated testing with Student’s t-test.

References

Felson DT, Cupples LA, Meenan RF. Misuse of statistical methods in Arthritis and Rheumatism. 1982 versus 1967-68. Arthritis Rheum 1984;27:1018-1022.